function:Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Associates with TRAF1, TRAF2, TRAF3 and TRAF5. Interacts with LINGO1.,tissue specificity:Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.,
Membrane ; Single-pass type I membrane protein .
Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes.
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