domain:The Nanos-type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein.,function:Required to support proliferation and self-renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3'-UTR of mRNA targets. Essential for spermatogonia formation.,similarity:Belongs to the nanos family.,similarity:Contains 1 nanos-type zinc finger.,
Cytoplasm . Cytoplasm, P-body . Cytoplasm, perinuclear region . Localizes at P-bodies during gonocyte development (By similarity). More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis. .
Testis and ovary. Expression found in several spermatogenic stages: in cells on the periphery of the tubules which could correspond to spermatogonia, in spermatocytes and in round spermatids (at protein level).
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