function:May have a function in cell adhesion and/or receptor signaling.,PTM:N-glycosylated.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed in pancreas, skeletal muscle, brain, and heart.,
Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane . Cell junction, focal adhesion . Secreted, extracellular space, extracellular matrix . Microsome membrane . Secreted . Cell junction, synapse, synaptosome . Proteolytic cleavage gives rise to a shedded ectodomain. .
Expressed in pancreas, skeletal muscle, brain, and heart.