domain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,function:Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
[Isoform 1]: Cytoplasm . Membrane; Peripheral membrane protein ; Cytoplasmic side .; [Isoform 2]: Cytoplasm . Localized close to nucleus on the apical side of both normal and neoplastic cells. .
Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level).
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