catalytic activity:Peptidylproline (omega=180) = peptidylproline (omega=0).,enzyme regulation:Inhibited preferentially by rapamycin over FK506.,function:FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.,similarity:Belongs to the FKBP-type PPIase family.,similarity:Contains 1 PPIase FKBP-type domain.,
Nucleus.
Human small intestine,Skeletal muscle,Skin,Thymus,
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