cofactor:Pyridoxal phosphate.,function:Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate.,similarity:Belongs to the serine/threonine dehydratase family.,
[Isoform SOFAT]: Secreted. Secreted by activated T-cells via a calcineurin-independent pathway.
Brain,Colon,Ovarian carcinoma,Skin,Tongue,
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