developmental stage:Down-regulated in haemopoietic progenitor cells undergoing differentiation and hemoglobinization. Abundant in fetal liver.,function:Exports cytoplasmic heme. May be required to protect developing erythroid cells from heme toxicity. Causes susceptibility to FeLV-C in vitro.,similarity:Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family.,tissue specificity:Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney.,
[Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Mitochondrion membrane ; Multi-pass membrane protein .
Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney.
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