function:Orphan receptor.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus. Also expressed in testis. Low expression in many other tissues.,
Cell membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Colocalizes with ARRB2/beta-arrestin-2 in the endosome (PubMed:28827538). .
Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus (PubMed:11690637, PubMed:29226084). Also expressed in testis (PubMed:11690637, PubMed:29226084) and T cells, B cells, and monocyte (PubMed:29226084). Low expression in many other tissues (PubMed:11690637, PubMed:29226084). Widely expressed in the hippocampus (at protein level).