ITSN2 Polyclonal Antibody

alternative products:Additional isoforms seem to exist,function:Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles.,miscellaneous:Overexpression results in the inhibition of the transferrin uptake and the blockage of the clathrin-mediated endocytosis.,similarity:Contains 1 C2 domain.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PH domain.,similarity:Contains 2 EF-hand domains.,similarity:Contains 2 EH domains.,similarity:Contains 5 SH3 domains.,subunit:Belongs to a complex that may contain multimers of ITSN1, ITSN2 and EPS15, and different partners according to the step in the endocytic process.,tissue specificity:Ubiquitous. Isoform 1 is primarily expressed in adult heart and liver.,