catalytic activity:ATP + (R)-5-phosphomevalonate = ADP + (R)-5-diphosphomevalonate.,induction:By sterol.,pathway:Isoprenoid biosynthesis; isopentenyl-PP biosynthesis via mevalonic acid pathway; isopentenyl-PP from (R)-mevalonic acid: step 2/3.,subunit:Monomer.,tissue specificity:Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta, and lung.,
Cytoplasm, cytosol .
Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung.
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