function:Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution.,similarity:Belongs to the gamma type-C retroviral envelope protein family.,
[Endogenous retroviral envelope protein HEMO]: Cell membrane ; Single-pass type I membrane protein . This uncleaved form present at the cell surface represents the major form (PubMed:28739914). .; [Endogenous retroviral envelope protein HEMO, secreted form]: Secreted . This secreted form, which is released in the extracellular medium following cleavage, constitutes a minor form (PubMed:28739914). .
Expressed at high level in the placenta and stem cells (at protein level) (PubMed:28739914). Also expressed in the kidney but at a lower level (PubMed:28739914). Endogenous retroviral envelope protein HEMO, secreted form: Present in the blood of pregnant women (at protein level) (PubMed:28739914).
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